N-T-BUTYLOXYCARBONYL-1,6-HEXAMETHYLENEDIAMINE HYDROCHLORIDE - Names and Identifiers
Name | N-boc-1,6-diamino-hexane hydrochloride
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Synonyms | Boc-1,6-Diaminohexane·HCl N-T-BOC-1,6-DIAMINOHEXANE HCL N-T-BOC-HEXAMETHYLENDIAMINE HCL N-Boc-1,6-diaminohexane hydrochloride N-BOC-1,6-Hexanediamine hydrochloride N-boc-1,6-diamino-hexane hydrochloride tert-butyl (6-aminohexyl)carbamate hydrochloride tert-butyl N-(6-aminohexyl)carbamate hydrochlorid tert-Butyl N-(6-aminohexyl)carbamate hydrochloride tert-butyl (6-aminohexyl)carbamate monohydrochloride N-tert-Butoxycarbonyl-1,6-diaminohexane hydrochloride N-TERT-BUTOXYCARBONYL-1,6-HEXANEDIAMINE HYDROCHLORIDE N-tert.-Butoxycarbonyl-1,6-hexanediamine hydrochloride N-T-BUTYLOXYCARBONYL-1,6-HEXAMETHYLENEDIAMINE HYDROCHLORIDE N-TERT-BUTYLOXYCARBONYL-1,6-HEXAMETHYLENEDIAMINE HYDROCHLORIDE N-Boc-1,6-hexanediamine hydrochloride~N-tert-Butoxycarbonyl-1,6-diaminohexane hydrochloride~tert-Butyl N-(6-aminohexyl)carbamate hydrochloride
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CAS | 65915-94-8
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EINECS | 265-976-4 |
InChI | InChI=1/C11H24N2O2.ClH/c1-11(2,3)15-10(14)13-9-7-5-4-6-8-12;/h4-9,12H2,1-3H3,(H,13,14);1H |
N-T-BUTYLOXYCARBONYL-1,6-HEXAMETHYLENEDIAMINE HYDROCHLORIDE - Physico-chemical Properties
Molecular Formula | C11H25ClN2O2
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Molar Mass | 252.78 |
Melting Point | 162-164°C(lit.) |
Boling Point | 325.3°C at 760 mmHg |
Flash Point | 150.5°C |
Vapor Presure | 0.000233mmHg at 25°C |
Appearance | Crystalline powder |
Color | White to cream |
BRN | 3631740 |
Storage Condition | 2-8°C |
Sensitive | Hygroscopic |
MDL | MFCD00039072 |
Use | Reagents for the introduction of the C6 spacer arm. |
N-T-BUTYLOXYCARBONYL-1,6-HEXAMETHYLENEDIAMINE HYDROCHLORIDE - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
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WGK Germany | 3 |
HS Code | 29241900 |
N-T-BUTYLOXYCARBONYL-1,6-HEXAMETHYLENEDIAMINE HYDROCHLORIDE - Introduction
N-boc-1,6-diamino-hexane hydrochloride, also known as N-boc-1,6-diamino-hexane hydrochloride, is an organic compound. Its chemical formula is C12H27ClN2O2.
Nature:
N-boc-1,6-diamino-hexane hydrochloride is a white to off-white solid powder with a special odor. Its solubility in the solvent is good, can be dissolved in water, alcohol and ether solvents.
Use:
N-boc-1,6-diamino-hexane hydrochloride is a commonly used organic synthesis intermediate. It is often used in the synthesis of other drug molecules or organic compounds, especially for the synthesis of biologically active natural products and drug lead compounds.
Preparation Method:
N-boc-1,6-diamino-hexane hydrochloride can be obtained by reacting 1,6-diaminohexane with a Boc acidifying agent. 1,6-Diaminohexane is first reacted with dimethylcarbonic anhydride (DMC) to give 1,6-diaminohexane dicarboxylic acid dimethyl ester, which is then reacted with a Boc acidifying agent such as tert-butyldioxyphosphonate under basic conditions to give N-Boc-1, 6-diaminohexane.
Safety Information:
N-boc-1, the specific safety information of the 6-diamino-hexane hydrochloride should be evaluated according to the technical data provided by the manufacturer. As an organic compound, it may cause irritation, allergies and other adverse reactions to the human body. When using or processing, take appropriate protective measures to avoid contact with skin, eyes and respiratory tract, and maintain good ventilation conditions. At the same time, attention should be paid to fire prevention and static control during storage and handling.
Last Update:2024-04-09 21:11:58